KL044, CAS [[1801856-93-8]]

Product Overview

• Article Name: KL044, CAS [[1801856-93-8]]
• Biozol Catalog Number: FBM-10-3911
• Supplier Catalog Number: 10-3911
• Alternative Catalog Number: FBM-10-3911-5MG, FBM-10-3911-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-Carbazol-9-yl-N-(2-chloro-6-cyanophenyl)acetamide

Product Description

Cryptochrome stabilizer

Product Properties

• Molecular Weight: 359.81
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1801856-93-8]
• Formula: C21H14ClN3O

Application Notes

• Application Notes: Potent stabilizer of the circadian clock protein cryptochrome (CRY).1 It lengthened the circadian period and repressed Per2 activity in reporter assays with 10-fold more potency than KL001 (Cat 10-1411). KL044 inhibited melanogenesis and melanosome transport via suppression of the cAMP/PKA/CREB pathway.2