BIBR1532, CAS [[321674-73-1]]

Product Overview

• Article Name: BIBR1532, CAS [[321674-73-1]]
• Biozol Catalog Number: FBM-10-3920
• Supplier Catalog Number: 10-3920
• Alternative Catalog Number: FBM-10-3920-5MG,FBM-10-3920-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Telomerase inhibitor

Product Properties

• Molecular Weight: 331.37
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [321674-73-1]
• Formula: C21H17NO3

Application Notes

• Application Notes: Non-competitive specific inhibitor of telomerase (IC50 = 93 nM), targeting telomerase reverse transcriptase (hTERT).1,2 Induces apoptosis in MCF-7 breast cancer cells and breast cancer stem cells3 and affected the epithelial mesenchymal transition in breast cancer stem cells4. BIBR1532 eliminated pancreatic stem cells via DNA damage and apoptosis in primary patient-derived samples.5 It significantly inhibited cell proliferation and induced apoptosis in acute myeloid leukemia stem cells.6