Chemical Name: 1-Cyclopropyl-6-fluoro-4-oxo-7-(4-(4-(trifluoromethyl)phenyl)carbamothioyl)piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid
Bacterial DNA repair inhibitor
Molecular Weight:
534.53
Purity:
98% by TLC NMR (Conforms)
Form:
White solid
CAS Number:
[1458674-25-3]
Formula:
C25H22F4N4O5S
Application Notes:
Potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50 = 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.
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