WX-02-37, CAS [[3020765-61-8]]

Catalog Number: FBM-10-3968
Article Name: WX-02-37, CAS [[3020765-61-8]]
Biozol Catalog Number: FBM-10-3968
Supplier Catalog Number: 10-3968
Alternative Catalog Number: FBM-10-3968-5MG, FBM-10-3968-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: (1R,3R)-2-Acryloyl-1-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide
SARM1 inhibitor
Molecular Weight: 429.48
Purity: 98% by HPLC NMR (Conforms)
Form: Pale yellow solid
CAS Number: [3020765-61-8]
Formula: C25H23N3O4
Application Notes: WX-02-37 is an allosteric, covalent SARM1 inhibitor (IC50 = 1.5 µM). It inhibited SARM1-dependent cADPR production in the human cell lines SH-SY5Y and 22Rv1. WX-02-37 protected mice from vacor- and vincristine-induced neurite degeneration.