Chemical Name: 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one, beta-D-N4-hydroxycytidine. Alternate Names: beta-D-N4-hydroxycytidine, EIDD-1931
Antiviral
Molecular Weight:
259.22
Purity:
98% by HPLC NMR (Conforms)
Form:
White solid
CAS Number:
[3258-02-4]
Formula:
C9H13N3O6
Application Notes:
N4-Hydroxycytidine was originally identified as a mutagen effecting AT to GC base-pair transitions.1 It has also been found to have antiviral properties against a broad range of viruses including hepatitis C2, norovirus3, Ebola virus4, Chikungunya virus5, influenza and respiratory syncytial viruses6, and importantly, coronaviruses.7,8 N4-hydroxycytidine is the active molecule in the antiviral pro-drug clinical candidate EIDD-2801.9
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