Cefcapene pivoxil, CAS [[147816-24-8]]

Product Overview

• Article Name: Cefcapene pivoxil, CAS [[147816-24-8]]
• Biozol Catalog Number: FBM-10-3972
• Supplier Catalog Number: 10-3972
• Alternative Catalog Number: FBM-10-3972-20MG, FBM-10-3972-100MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2,2-Dimethylpropanoyloxymethyl (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylatehydratehydrochloride. Alternate Names: S-1108

Product Description

Antibiotic/Gasdermin D inhibitor

Product Properties

• Molecular Weight: 622.11
• Purity: >98% by HPLC, NMR (conforms)
• Form: Off-white to beige solid
• CAS Number: [147816-24-8]
• Formula: C23H29N5O8S2HClH2O

Application Notes

• Application Notes: Cefcapene pivoxil is a pivalate ester prodrug form of the third generation cephalosporin Cefcapene. Displays broad-spectrum antibacterial activity against both Gram-negative and -positive bacteria including S. aureus.1 Cefcapene pivoxil potently suppresses gasdermin D-mediated pyroptosis via targeting of the oligomerization interface I.2 Active in vivo in a mouse model of sepsis. Cefcapene pivoxil acts synergistically with another gasdermin D inhibitor, SCR-1481B1 (Cat 10-3971), and a PD-L1 antibody to significantly enhance the antitumor activity of anti-PD-L1 therapy.