Thiothixene, CAS [[3313-26-6]]

Catalog Number: FBM-10-3998
Article Name: Thiothixene, CAS [[3313-26-6]]
Biozol Catalog Number: FBM-10-3998
Supplier Catalog Number: 10-3998
Alternative Catalog Number: FBM-10-3998-5MG, FBM-10-3998-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: ((Z)-N,N-Dimethyl-9-[3-(4-methyl-1-iperazinyl)propylidene]thioxanthene-2-sulfonamide
Efferocytosis stimulator / Typical antipsychotic
Molecular Weight: 443.62
Purity: >98% by HPLC, NMR (Conforms)
Form: White solid
CAS Number: [3313-26-6]
Formula: C23H29N3O2S2
Application Notes: Thiothixene is a clinically useful typical antipsychotic.1 It acts as an antagonist at multiple receptors including dopamine D2 and D3 (sub-nanomolar), histamine H1, serotonin 5-HT7, and alpha1/2-adrenergic. Thiothixene stimulates efferocytosis, the phagocytic removal of apoptotic cells by macrophages, via increased expression of the retinol-binding protein receptor Stra6L leading to arginase 1 production.2 A potential new use for an old drug to facilitate the removal of diseased tissue.