Chemical Name: 2-Hydroxy-6-pentadecylbenzoic acid. Alternate Names: 6-Pentadecylsalicylic acid, 6-PDSA
HAT inhibitor
Molecular Weight:
348.52
Purity:
98% by HPLC, NMR (Conforms)
Form:
White solid
CAS Number:
[16611-84-0]
Formula:
C22H36O3
Application Notes:
Anacardic acid is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50s = 8.5 and 5.0 µM respectively).1 Anacardic acid sensitizes cancer cells to ionizing radiation2 and suppresses proteins involved in invasion and angiogenesis (Src/FAK/Rho GTPases3 and MMPs 2 (IC50 = 11.11 µM)4 and 9). It inhibits both inducible and constitutive NF-kappaB activation.5
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