RGFP966, CAS [[1357389-11-7]]

Catalog Number: FBM-10-4029
Article Name: RGFP966, CAS [[1357389-11-7]]
Biozol Catalog Number: FBM-10-4029
Supplier Catalog Number: 10-4029
Alternative Catalog Number: FBM-10-4029-5MG, FBM-10-4029-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: (2E)-N-(2-Amino-4-fluorophenyl)-3-[(2E)-1-(3-phenyl-2-propen-1-yl)-1H-pyrazol-4-yl]-2-propenamide
HDAC3 inhibitor
Molecular Weight: 362.40
Purity: 98%, NMR (Conforms)
Form: Off-white solid
CAS Number: [1357389-11-7]
Formula: C21H19FN4O
Application Notes: RGFP966 is a selective inhibitor of HDAC3 (IC50 = 80 nM, no other HDACs inhibited at 15µM).1 It facilitates the extinction of cocaine-seeking behavior in mice and transforms subthreshold learning events into robust long-term memory, suggesting a potential therapeutic target for memory enhancement and neurodegenerative diseases.1-5