EPZ015666, CAS [[1616391-65-1]]

Product Overview

• Article Name: EPZ015666, CAS [[1616391-65-1]]
• Biozol Catalog Number: FBM-10-4031
• Supplier Catalog Number: 10-4031
• Alternative Catalog Number: FBM-10-4031-5MG, FBM-10-4031-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (S)-N-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide

Product Description

PRMT5 inhibitor

Product Properties

• Molecular Weight: 383.44
• Purity: 98% by HPLC NMR (conforms)
• Form: White solid
• CAS Number: [1616391-65-1]
• Formula: C20H25N5O3

Application Notes

• Application Notes: EPZ015666 is a selective and potent (IC50 = 22nM) inhibitor of arginine methyltransferase 5 (PRMT5).1,2 PRMT5 inhibition with EPZ015666 potently suppressed in vivo glioblastoma tumors3 and significantly inhibited the growth of multiple myeloma cell lines4.