Chemical Name: (1R)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl-1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride
Methyltransferase SETD7 inhibitor
Molecular Weight:
535.98
Purity:
98% by TLC NMR (Conforms)
Form:
White solid
CAS Number:
[1627607-87-7]
Formula:
C23H25F4N3O3S HCl
Application Notes:
Potent (IC50 = 2nM) and selective SAM-dependent inhibitor of the lysine methyltransferase SETD7.1 It alters Hippo pathway signaling in MCF7 cells by altering YAP nuclear localization in a SETD7-dependent manner.
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