PFI-3, CAS [[1819363-80-8]]

Product Overview

• Article Name: PFI-3, CAS [[1819363-80-8]]
• Biozol Catalog Number: FBM-10-4034
• Supplier Catalog Number: 10-4034
• Alternative Catalog Number: FBM-10-4034-5MG, FBM-10-4034-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (2E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-(pyridine-2-yl)-2,5-diazabicyclo{2.2.1]heptan-2-yl]prop-2-en-1-one

Product Description

Family VIII bromodomain inhibitor

Product Properties

• Molecular Weight: 321.37
• Purity: 98%, NMR (Conforms)
• Form: Yellow solid
• CAS Number: [1819363-80-8]
• Formula: C19H19N3O2

Application Notes

• Application Notes: PFI-3 (1819363-80-8) is a selective inhibitor of family VIII bromodomains PB1(5), SMARCA2, and SMARCA4.1 It showed complete selectivity over all non-family VIII bromodomains. PFI-3 blocked adipogenesis in C3H10T1/2 mesenchymal cells at 20µM.Treatment of embryonic stem cells with PFI-3 led to deprivation of stemness and deregulated lineage specificity. Differentiation of trophoblast stem cells in the presence of PFI-3 was enhanced.2 Cell permeable.