Chemical Name: N2-(3-(Dimethylamino)propyl)-6-phenyl-N4-(piperidin-4-ylmethyl)quinazoline-2,4-diamine
RING ligase TRIM58 ligand
Molecular Weight:
418.59
Purity:
>98% HPLC, NMR (Conforms)
Form:
Off-white solid
Formula:
C25H34N6
Application Notes:
TRIM-473 is a ligand (EC50 = 5.3 µM) for the PRY-SPRY domain of the RING ligase TRIM58. An interesting new tool for the development of heterobifunctional degraders of this novel tissue-selective (erythroid precursor cells) ligase.
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