Chemical Name: 2,2-Diphenyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
Nav1.1/1.3 inhibitor (selective)
Molecular Weight:
449.54
Purity:
98% by TLC , NMR (Conforms)
Form:
Off-white to beige solid
CAS Number:
[313254-51-2]
Formula:
C23H19N3O3S2
Application Notes:
Selective Nav1.1/1.3 inhibitor (hIC50s = 23 and 13 nM respectively, also selective for dog, monkey, and mouse, but not rat).1 It exclusively shifts voltage dependence to more negative voltages and accelerates entry into slow activation.2
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