C-176, CAS [[314054-00-7]]

Product Overview

• Article Name: C-176, CAS [[314054-00-7]]
• Biozol Catalog Number: FBM-10-4130
• Supplier Catalog Number: 10-4130
• Alternative Catalog Number: FBM-10-4130-10MG, FBM-10-4130-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-(4-Iodophenyl)-5-nitrofuran-2-carboxamide

Product Description

STING antagonist

Product Properties

• Molecular Weight: 358.09
• Purity: 98%
• Form: Brown or yellow solid
• CAS Number: [314054-00-7]
• Formula: C11H7IN2O4

Application Notes

• Application Notes: C-176 is an inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. Treatment of Trex-/- mice with C-176 resulted in a significant reduction in serum levels of Type I Interferons and amelioration of systemic inflammation.