Chemical Name: 5-(Furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide
Wnt/ß-Catenin pathway activator
Molecular Weight:
286.29
Purity:
>98% by HPLC NMR (Conforms)
Form:
Beige solid
CAS Number:
[909089-13-0]
Formula:
C14H14N4O3
Application Notes:
SKL2001 is a Wnt/ß-catenin pathway activator that disrupts the Axin/ß-catenin interaction leading to ß-catenin stabilization.1 It suppressed colon cancer spheroid growth via regulation of the E-cadherin/ß-catenin complex.2 A commonly used reagent to reactivate or rescue the Wnt/ß-Catenin signaling pathway.3,4
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