Tiagabine hydrochloiride, CAS [[145821-59-6]]

Product Overview

• Article Name: Tiagabine hydrochloiride, CAS [[145821-59-6]]
• Biozol Catalog Number: FBM-10-4384
• Supplier Catalog Number: 10-4384
• Alternative Catalog Number: FBM-10-4384-10MG, FBM-10-4384-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (3R)-1-[4,4-Bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid hydrochloride. Alternate Names: NO-325

Product Description

GABA transporter 1 (GAT1) inhibitor

Product Properties

• Molecular Weight: 412.00
• Purity: >98% by HPLC NMR (Conforms)
• Form: Off white or beige solid
• CAS Number: [145821-59-6]
• Formula: C20H25NO2S2HCl

Application Notes

• Application Notes: Tiagabine is a clinically useful anticonvulsant.1 It is also used to treat anxiety/panic disorder2 and neuropathic pain3. Tiagabine inhibits GABA-reuptake (IC50 [3H]GABA uptake = 67 nM) via inhibiting GABA transporter 1(GAT1) blocking both neuronal and glial GABA re-uptake.4,5