MIF20, CAS [[1191288-81-9]]

Product Overview

• Article Name: MIF20, CAS [[1191288-81-9]]
• Biozol Catalog Number: FBM-10-4393
• Supplier Catalog Number: 10-4393
• Alternative Catalog Number: FBM-10-4393-10MG, FBM-10-4393-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-(4-(Pyridin-3-yl)-1H-1,2,3-triazol-1-yl)phenol

Product Description

MIF agonist

Product Properties

• Molecular Weight: 238.25
• Purity: >98% by HPLC NMR (Conforms)
• Form: Olive green solid
• CAS Number: [1191288-81-9]
• Formula: C13H10N4O

Application Notes

• Application Notes: MIF20 is a macrophage inhibitory factor (MIF) agonist (2.5 fold increase in MIF bound to its receptor 500 nM).1 It augments MIF-dependent AMPK signaling and limits ischemic cardiac injury. MIF20 protected the heart from ischemia-reperfusion injury via MIF-mediated activation of AMPK.2 It decreased infarct size and preserved systolic function. MIF20 also augments protective metabolic responses by reducing the NADH/NAD ratio leading to a decrease in the accumulation of reactive oxygen species.