Selpercatinib, CAS [[2152628-33-4]]

Product Overview

• Article Name: Selpercatinib, CAS [[2152628-33-4]]
• Biozol Catalog Number: FBM-10-4407
• Supplier Catalog Number: 10-4407
• Alternative Catalog Number: FBM-10-4407-5MG, FBM-10-4407-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 6-(2-Hydroxy-2-methylpropoxy)-4-(6-(6-((6-methyoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridine-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile. Alternate Names: LOXO-292

Product Description

Potent and selective RET kinase inhibitor

Product Properties

• Molecular Weight: 525.61
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [2152628-33-4]
• Formula: C29H31N7O3

Application Notes

• Application Notes: Selpercatinib is a potent (IC50 = 0.45 nM)1 and selective inhibitor of RET kinase.2 Clinically relevant for the treatment of RET-altered non-small cell lung cancer3 and certain thyroid cancers4.