TH257, CAS [[2244678-29-1]]

Product Overview

• Article Name: TH257, CAS [[2244678-29-1]]
• Biozol Catalog Number: FBM-10-4418
• Supplier Catalog Number: 10-4418
• Alternative Catalog Number: FBM-10-4418-5MG, FBM-10-4418-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide

Product Description

Allosteric LIM kinase inhibitor

Product Properties

• Molecular Weight: 422.54
• Purity: >98% by HPLC NMR (Conforms)
• Form: White to off-white glassy solid
• CAS Number: [2244678-29-1]
• Formula: C24H26N2O3S

Application Notes

• Application Notes: TH257 is a potent (IC50s = 238 nM (LIMK1) and 91 nM (LIMK2)) and highly selective (no off-targets against 468 kinases) allosteric inhibitor of LIM kinase 1/2.1 It inhibited neurite outgrowth in N1E-115 cells in a dose-dependent manner.