Chemical Name: 1-Cyclobutyl-N-(3-(dimethylamino)propyl)-2-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazole-6-carboxamide
ALK1/2 inhibitor
Molecular Weight:
466.58
Purity:
>98% by HPLC NMR (conforms)
Form:
White solid
CAS Number:
[3052084-77-9]
Formula:
C26H34N4O4
Application Notes:
CDD-2789 is a potent (IC50 = 3.9 nM ALK1, 2.1 nM ALK2) and selective ALK1/2 inhibitor. It attenuated activin A and BMP-induced phosphorylated SMAD1/5 activation in fibroblasts in a dose-dependent manner.
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