Chemical Name: N-(3R)-1-Azabicyclo[2.2.2}oct-3-yl-4-chlorobenzamide
nAChR agonist
Molecular Weight:
264.75
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[123464-89-1]
Formula:
C14H17ClN2O
Application Notes:
PNU 282987 is a selective alpha7 nicotinic acetylcholine receptor (nAChR) agonist (Ki = 26 nM).1 The alpha7 nAChR is a potential therapeutic target of cognitive deficits in diseases such as Alzheimers, Parkinsons, schizophrenia, and attention deficit disorders - agonism of this receptor with PNU 282987 has shown potential to ameliorate these deficits.2-5
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