Chemical Name: 27-Hydroxycholesterol, 5,25R-Cholesten-3beta,26-diol
Cholesterol metabolite
Molecular Weight:
402.66
Purity:
98% by HPLC, NMR (Conforms)
Form:
White solid
CAS Number:
[20380-11-4]
Formula:
C27H46O2
Application Notes:
Metabolite resulting from the action of sterol 27-hydroxylase on cholesterol. Concentrations of 27-hydroxycholesterol are elevated in patients with Alzheimers disease and mild cognitive impairment.1,2 Endogenous selective estrogen receptor modulator3 and ligand for the liver X receptor(EC50 = 85nM for LXRalpha and 71nM for LXRbeta)4.
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