Chemical Name: [5-[4-[(5-Methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol. Alternate Names: CID 44968231
Clk4 inhibitor
Molecular Weight:
335.36
Purity:
>98% by HPLC NMR (Conforms)
Form:
White solid
CAS Number:
[1285702-20-6]
Formula:
C19H17N2O3
Application Notes:
ML167 is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) - IC50 = 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 µM), Clk2(1.65µM), Clk3(>10µM), Dyrk1A(>10µM), and Dyrk1B(4.4 µM).
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