Chemical Name: 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate)
Glucose transport inhibitor
Molecular Weight:
368.31
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[1223397-11-2]
Formula:
C20H13FO6
Application Notes:
WZB117 is an inhibitor of Glucose Transporter 1 (GLUT1). It inhibited cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells with an IC50 of approximately 10 µM. Daily intraperitoneal injection of WZB117 at 10mg/kg resulted in 70% reduction in tumor volume of human A549 lung cancer grafted on nude mice
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