ABX-1431, CAS [[1446817-84-0]]

Product Overview

• Article Name: ABX-1431, CAS [[1446817-84-0]]
• Biozol Catalog Number: FBM-10-4596
• Supplier Catalog Number: 10-4596
• Alternative Catalog Number: FBM-10-4596-10MG, FBM-10-4596-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1,1,1,3,3,3-Hexafluoropropan-2-yl-4-[[2-(pyrrolidin-1-yl)-4-(trifluoromethyl)phenyl]methyl]piperazine-1-carboxylate

Product Description

MAGL inhibitor

Product Properties

• Molecular Weight: 507.40
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1446817-84-0]
• Formula: C20H22F9N3O2

Application Notes

• Application Notes: Potent (IC50 = 14 nM in vitro, 2.2 nM in human PC3 cells) and very selective (>100-fold over hABHD6, >200-fold over hPLA2G7) inhibitor of monoacylglycerol lipase (MAGL).1 Active in a rat formalin pain test at 3mg/kg. Orally bioavailable and CNS penetrant.