Chemical Name: 5-Ethynyluracil. Alternate Names: GW776C85
Dihydropyrimidine dehydrogenase inhibitor
Molecular Weight:
136.11
Purity:
97% by HPLC, NMR (conforms)
Form:
Yellow solid
CAS Number:
[59989-18-3]
Formula:
C6H4N2O2
Application Notes:
Eniluracil is an irreversible dihydropyrimidine dehydrogenase (DPD) inhibitor.1,2,3 DPD is involved in the degradation of pyrimidine-based chemotherapeutic drugs such as 5-fluorouracil (5-FU). Eniluracil has been used along with 5-FU to prolong circulating concentrations of the drug.
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