Chemical Name: 6-Chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]purin-2-amine. Alternate Names: CNF2024
HSP90 inhibitor
Molecular Weight:
318.76
Purity:
98% by HPLC NMR (Conforms)
Form:
White solid
CAS Number:
[848695-25-0]
Formula:
C14H15ClN6O
Application Notes:
Potent HSP90 inhibitor (IC50 = 30 nM HER-2 degradation).1 It inhibited the proliferation of MCF7 and BT474 breast cancer cell lines (IC50 = 100 nM for each). BIIB021 has shown efficacy as a therapeutic in multiple cancer models.2-5
* VAT and and shipping costs not included. Errors and price changes excepted