Chemical Name: Isopropyl (1-((5-chloro-8-hydroxyquinolin-7-yl)methyl)piperidin-4-yl)carbamate
Kir7.1/6.2 blocker
Molecular Weight:
377.87
Purity:
>98% by HPLC NMR (Conforms)
Form:
White solid
CAS Number:
[1928763-08-9]
Formula:
C19H24ClN3O3
Application Notes:
ML418 is a blocker of the inward rectifier potassium channels Kir7.1 (IC50 = 310nM) and Kir6.2 (equipotent) with metabolic and pharmacokinetic parameters suitable for in vivo research.1 Greater than 23-fold selectivity over Kir1.1, Kir2.1, Kir2.2, Kir2.3, Kir4.1.
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