A1899, CAS [[498577-46-1]]

Catalog Number: FBM-10-4656
Article Name: A1899, CAS [[498577-46-1]]
Biozol Catalog Number: FBM-10-4656
Supplier Catalog Number: 10-4656
Alternative Catalog Number: FBM-10-4656-5MG,FBM-10-4656-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: N-[(2,4-Difluorophenyl)methyl]-2-[2-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]phenyl]benzamide
Potent and selective K2P3.1 blocker
Molecular Weight: 500.55
Purity: >97% by HPLC NMR (Conforms)
Form: Off-white solid
CAS Number: [498577-46-1]
Formula: C30H26F2N2O3
Application Notes: A1899 is a potent and selective blocker of the two-pore domain potassium channels K2P3.1 (TASK-1, IC50 = 7 nM) and K2P9.1 (TASK-3, IC50 = 70 nM).1 It stimulated breathing in isoflurane-anesthetized rats.2
10-4656