Chemical Name: tert-Butyl 4-(1-adamantylamino)-3-(pyrimidin-5-ylmethylideneamino)benzoate
Lipid peroxidation inhibitor
Molecular Weight:
432.57
Purity:
>98% by TLC (NMR Conforms)
Form:
Yellow solid
CAS Number:
[1793052-96-6]
Formula:
C26H32N4O2
Application Notes:
SRS16-86 is a third generation ferrostatin derivative with greater metabolic and plasma stability for in vivo studies. It protected mice in a renal severe ischemia-reperfusion injury model via inhibition of ferroptosis.1 SRS16-86 enhanced functional recovery after spinal cord injury in a rat model via upregulation of GPX4, GSH, and xCT as well as downregulation of lipid peroxidation marker 4-hydroxynonenal.2
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