CBR-470-1, CAS [[2416095-06-0]]

Product Overview

• Article Name: CBR-470-1, CAS [[2416095-06-0]]
• Biozol Catalog Number: FBM-10-4680
• Supplier Catalog Number: 10-4680
• Alternative Catalog Number: FBM-10-4680-5MG, FBM-10-4680-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: trans-4-(4-Chlorophenyl)sulfonyl-N-(2-methylpropyl)-1,1-dioxothiolan-3-amine

Product Description

NRF2 signaling activator

Product Properties

• Molecular Weight: 365.89
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [2416095-06-0]
• Formula: C14H20ClNO4S2

Application Notes

• Application Notes: Activator of NRF2 signaling (EC50 ~ 1 µM cellular ARE-LUC assay).1 It inhibits phosphoglycerate kinase 1 leading to a build-up of methylglyoxal which inactivates KEAP1. It protected SH-SY5Y neuronal cells from MPP+ induced oxidative injury via activation of NRF2 signaling.2