Selonsertib, CAS [[1448428-04-3]]

Product Overview

• Article Name: Selonsertib, CAS [[1448428-04-3]]
• Biozol Catalog Number: FBM-10-4696
• Supplier Catalog Number: 10-4696
• Alternative Catalog Number: FBM-10-4696-5MG, FBM-10-4696-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-(4-Cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl)-1,2,4-triazol-3-yl)pyridine-2-yl]benzamide. Alternate Names: GS-4997

Product Description

ASK1 inhibitor

Product Properties

• Molecular Weight: 445.50
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1448428-04-3]
• Formula: C24H24FN7O

Application Notes

• Application Notes: Potent Apoptosis signal-regulating kinase 1 (ASK1) inhibitor (pIC50 = 8.3)1 found to improve metabolic parameters in nonalcoholic steatohepatitis, reduce hepatic steatosis, inflammation, and fibrosis2-4. Selonsertib suppressed the efflux function of multidrug resistance (MDR) transporters ABCB1 and ABCG2.5