Chemical Name: (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol. Alternate Names: CCG-168
mTOR kinase inhibitor
Molecular Weight:
465.54
Purity:
99% by HPLC NMR (Conforms)
Form:
Yellow solid
CAS Number:
[1009298-09-2]
Formula:
C25H31N5O4
Application Notes:
AZD8055 is a potent and highly selective inhibitor of mammalian target of rapamycin kinase (mTOR) kinase (IC50 = 0.8 nM).1,2 mTOR acts as a nutrient/energy/redox sensor and a controller of protein synthesis - as such it is a very important target for cancer research. It has been investigated as a potential chemotherapeutic for various cancers.3-7
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