NVP-BGJ398, CAS [[872511-34-7]]

Product Overview

• Article Name: NVP-BGJ398, CAS [[872511-34-7]]
• Biozol Catalog Number: FBM-10-4817
• Supplier Catalog Number: 10-4817
• Alternative Catalog Number: FBM-10-4817-10MG, FBM-10-4817-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)-1-methylurea. Alternate Names: Infigratinib

Product Description

FGFR inhibitor (pan-spec)

Product Properties

• Molecular Weight: 560.48
• Purity: 99% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [872511-34-7]
• Formula: C26H31Cl2N7O3

Application Notes

• Application Notes: NVP-BGJ398 is a potent and selective pan-FGFR inhibitor (IC50 = 0.9nM, 1.4 nM, 1.0 nM, and 60 nM for FGFR1,2,3,4 respectively).1 It has also been used in a mouse model of Achondroplasia (most common form of dwarfism) to correct pathological hallmarks of this condition.2