Chemical Name: 2-[(2S)-1-[3-Ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol. Alternate Names: SCH 727965
CDK inhibitor
Molecular Weight:
396.50
Purity:
98% by HPLC NMR (Conforms)
Form:
Off-white to pale orange solid
CAS Number:
[779353-01-4]
Formula:
C21H28N6O2
Application Notes:
Dinaciclib is a potent and selective inhibitor of cyclin-dependent kinases CDK1, CDK2, CDK5, and CDK9 (IC50s respectively: 3 nM, 1 nM, 1 nM, and 4 nM).1,2 Active across multiple human cancer cell lines and in mouse xenograft models.3-9
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