Chemical Name: 8-((2-(1H-Indol-3-yl)ethyl)amino)-7-(4-fluorobenzyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione. Alternate Names: 7-[(4-Fluorophenyl)methyl]-8-[2-(1H-indol-3-yl)ethylamino]-1,3-dimethylpurine-2,6-dione
GPR18 agonist
Molecular Weight:
446.49
Purity:
>98% by HPLC NMR (Conforms)
Form:
White solid
CAS Number:
[885896-54-8]
Formula:
C24H23FN6O2
Application Notes:
PSB-KK1445 is a potent (EC50 = 45.4 nM human, 124 nM mouse) and highly selective (>200-fold over CB1, CB2, GPR55, and GPR183) GPR18 agonist. A new chemical tool to explore the role of GPR18 in cancer and immunology.
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