GRL-0617, CAS [[1093070-16-6]]

Product Overview

• Article Name: GRL-0617, CAS [[1093070-16-6]]
• Biozol Catalog Number: FBM-10-4965
• Supplier Catalog Number: 10-4965
• Alternative Catalog Number: FBM-10-4965-5MG, FBM-10-4965-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-Amino-2-methyl-N-(1R-naphthalen-1-yl-ethyl)benzamide

Product Description

SARS-CoV PLpro inhibitor

Product Properties

• Molecular Weight: 304.39
• Purity: 99% by HPLC NMR (Conforms)
• Form: Beige solid
• CAS Number: [1093070-16-6]
• Formula: C20H20N2O

Application Notes

• Application Notes: GRL-0617 is a potent (IC50 = 600 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL0617 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 15 µM). Inactive against human DUB-like proteases HAUSP, USP18, UCH-L1, UCH-L3, and PLP2.