Chemical Name: N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-3-methyl-1-[(1E)-2-(methylsulfonyl)ethenyl]butyl]-L-leucinamide. Alternate Names: ZL3VS, Z-Leu-Leu-Leu-VS
Proteasome inhibitor
Molecular Weight:
551.74
Purity:
>98% by TLC NMR (Conforms)
Form:
White solid
CAS Number:
[193482-47-2]
Formula:
C28H45N3O6S
Application Notes:
Z-Leu-Leu-Leu-vinylsulfone (193482-47-2) blocks the trypsin-like, chymotrypsin-like, and peptidylglutamyl peptidase activity in isolated proteasomes and in living cells via covalent modification of active site threonine residues.1,2
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