Brigatinib, CAS [[1197953-54-0]]

Product Overview

• Article Name: Brigatinib, CAS [[1197953-54-0]]
• Biozol Catalog Number: FBM-10-5034
• Supplier Catalog Number: 10-5034
• Alternative Catalog Number: FBM-10-5034-5MG, FBM-10-5034-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4- pyrimidinediamine. Alternate Names: AP26113

Product Description

pan-ALK inhibitor

Product Properties

• Molecular Weight: 584.02
• Purity: 98% by HPLC (NMR Conforms)
• Form: White or off-white solid
• CAS Number: [1197953-54-0]
• Formula: C29H39ClN7O2P

Application Notes

• Application Notes: A potent and selective pan-ALK inhibitor IC50=0.6 nM.1 Cells with ALK mutation L1196Q2 and the double mutation I1171S + G12693 remain sensitive to brigatinib. Clinically useful in non-small cell lung cancer.4