Chemical Name: 1-Amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
FSP1 inhibitor
Molecular Weight:
323.36
Purity:
>98% by TLC NMR (Conforms)
Form:
Yellow solid
CAS Number:
[150651-39-1]
Formula:
C20H13N5
Application Notes:
iFSP1 inhibits ferroptosis suppressor protein 1, inducing ferroptosis.1 iFSP1 synergizes with GPX4 inhibitors to initiate ferroptosis in cancer cells.1 It potently induced ferroptosis, which promoted innate and adaptive anti-tumor immune responses, in human hepatocellular carcinoma cells which overexpress FSP1.2 A useful tool for establishing ferroptotic cells in Alzheimers disease models.3
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