Histamine H2 antagonist, antiulcer and anti-inflammatory
Molecular Weight:
306.40
Purity:
98% by TLC NMR (Conforms)
Form:
Colorless to pale yellow oil
CAS Number:
[78273-80-0]
Formula:
C17H26N2O3
Application Notes:
A novel histamine H2 receptor antagonist.1 Suppresses inflammatory responses via inhibition of NFB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages.2 Clinically useful agent for prevention and healing of gastric and duodenal ulcers and bleeding.3 Attenuates degradation of extracellular matrix in osteoarthritis models by inactivating the NFkB pathway.4
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