SSAA09E1, CAS [[433212-75-0]]

Product Overview

• Article Name: SSAA09E1, CAS [[433212-75-0]]
• Biozol Catalog Number: FBM-10-5075
• Supplier Catalog Number: 10-5075
• Alternative Catalog Number: FBM-10-5075-5MG, FBM-10-5075-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: [(Z)-1-Thiophene-2-ylethylideneamino]thiourea

Product Description

SARS-CoV viral entry inhibitor

Product Properties

• Molecular Weight: 199.29
• Purity: >98% by TLC NMR (Conforms)
• Form: Beige solid
• CAS Number: [433212-75-0]
• Formula: C7H9N3S2

Application Notes

• Application Notes: SSAA09E1 (433212-75-0) is an inhibitor of SARS coronavirus (SARS-CoV) replication by blocking viral entry (EC50=6.7mM). SSAA09E1 was discovered by screening a chemical library for blocking of entry of HIV-1 pseudotyped with SARS-CoV surface glycoprotein S. The compound acts via inhibition of cathepsin L(IC50=5.33 mM), a host protease required for processing of SARS-S during viral entry. Cathepsin B is not inhibited.1 The compound was also shown to inhibit tyrosinase (IC50=0.14 mM).2