Chemical Name: 2,7-dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid, ethyl ester
ASK1 inhibitor
Molecular Weight:
319.31
Purity:
98% by TLC, NMR (Conforms)
Form:
Yellow solid
CAS Number:
[175026-96-7]
Formula:
C19H13NO4
Application Notes:
Potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1), Ki = 500 nM.1 Promotes survival of induced pluripotent stem cells.2 Improves neurological function after intracerebral hemorrhage in a mouse model.3 A highly useful inhibitor for probing the involvement of ASK1 in cellular physiology.4,5
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