Filgotinib, CAS [[1206161-97-8]]

Product Overview

• Article Name: Filgotinib, CAS [[1206161-97-8]]
• Biozol Catalog Number: FBM-10-5145
• Supplier Catalog Number: 10-5145
• Alternative Catalog Number: FBM-10-5145-5MG, FBM-10-5145-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-cyclopropanecarboxamide. Alternate Names: GLPG0634, GS-6034

Product Description

JAK1 inhibitor

Product Properties

• Molecular Weight: 425.50
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1206161-97-8]
• Formula: C21H23N5O3S

Application Notes

• Application Notes: Potent and selective JAK1 inhibitor (IC50s=10, 28, 810 and 116 nM for JAK1, JAK2, JAK3 and TYK2 respectively.2 Displays potent anti-inflammatory activity in various models.1,2 Effective as a monotherapy in patients with active rheumatoid arthritis.3 Reverses oncostatin M-mediated inhibition of rat stem Leydig cell differentiation.4