UNC0224, CAS [[1197196-48-7]]

Product Overview

• Article Name: UNC0224, CAS [[1197196-48-7]]
• Biozol Catalog Number: FBM-10-5216
• Supplier Catalog Number: 10-5216
• Alternative Catalog Number: FBM-10-5216-1MG, FBM-10-5216-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine

Product Description

G9a histone methyl transferase inhibitor

Product Properties

• Molecular Weight: 485.68
• Purity: >98% by TLC NMR (Conforms)
• Form: White to off-white solid
• CAS Number: [1197196-48-7]
• Formula: C26H43N7O2

Application Notes

• Application Notes: UNC0224 is a potent inhibitor of histone methyltransferases G9a / EHMT2 (IC50 = 15 nM) and GLP / EHMT1 (IC50 ~ 39 nM) but not SET7/9 and SET8.1-3 Has been employed, as part of a small molecule cocktail, to reprogram somatic cells to pluripotent stem cells.4