MitoBloCK-10, CAS [[394694-98-5]]

Product Overview

• Article Name: MitoBloCK-10, CAS [[394694-98-5]]
• Biozol Catalog Number: FBM-10-5324
• Supplier Catalog Number: 10-5324
• Alternative Catalog Number: FBM-10-5324-5MG, FBM-10-5324-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (E)-3-Fluoro-N-((5-nitrothiophen-2-yl)methylene)benzohydrazide. Alternate Names: MB-10

Product Description

TIMM44 blocker

Product Properties

• Molecular Weight: 293.27
• Purity: 98% by TLC, NMR (Conforms)
• Form: Yellow solid
• CAS Number: [394694-98-5]
• Formula: C12H8FN3O3S

Application Notes

• Application Notes: MitoBloCK-10 is a first in class TIMM44 blocker. Translocase of inner mitochondrial membrane 44 (TIMM44) is essential for maintaining function and integrity of mitochondria.1 It induced mitochondrial dysfunction and suppressed angiogenic activity in endothelial cells.1 Targeting TIMM44 by MitoBloCK-10 significantly inhibits bladder cancer cell growth in vitro and in vivo.2