Atazanavir, CAS [[198904-31-3]]

Catalog Number: FBM-10-5630
Article Name: Atazanavir, CAS [[198904-31-3]]
Biozol Catalog Number: FBM-10-5630
Supplier Catalog Number: 10-5630
Alternative Catalog Number: FBM-10-5630-10MG, FBM-10-5630-50MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: Methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate. Alternate Names: BMS 232632, CGP 73547, Latazanavir
HIV-1 protease inhibitor
Molecular Weight: 704.87
Purity: >98% by HPLC NMR (Conforms)
Form: White to off-white solid
CAS Number: [198904-31-3]
Formula: C38H52N6O7
Application Notes: An azapeptide-based inhibitor of HIV protease (Ki = 2.66 nM).1 Inhibits SARS-CoV-2 main protease (Ki = 703 nM), but not papain-like protease (Ki = 9.87 µM).2 Blocks SARS-CoV-2 replication and IL-6 / TNFalpha production in vitro.3 Also inhibits the liver enzyme UDP-glucuronyltransferase 1A1 (UGT1A1), IC50 = 160 nM for recombinant UGT1A1.4