Intelliscreen(TM) DNA Damage Inducers Mini-Library

Catalog Number: FBM-10-7330
Article Name: Intelliscreen(TM) DNA Damage Inducers Mini-Library
Biozol Catalog Number: FBM-10-7330
Supplier Catalog Number: 10-7330
Alternative Catalog Number: FBM-10-7330-1LIBRARY
Manufacturer: Focus Biomolecules
Category: Molekularbiologie
Comprises 25 compounds that induce DNA damage via different mechanisms
Form: Supplied as DMSO solution 10mM
Application Notes: DNA damage-inducing agents have been a cornerstone of cancer treatment for decades. DNA damage of cancer cells can lead to inhibition of cellular proliferation and induction of cell death. The IntelliscreenTM DNA Damage Inducers mini-library contains classes of agents including alkylating/platinum-based reagents that directly interact with DNA, antimetabolites that interfere with DNA replication and repair, topoisomerase inhibitors, and antitumor antibiotics which function through a variety of mechanisms including intercalation, alkylation, and ROS production.