Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions
Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl (pH8.0) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System:
E. coli
Form:
Lyophilized powder
Sequence:
N-terminal His-Tag, Asn46~Thr320 (NP_002244.1)
Application Notes:
Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) also known as kinase insert domain receptor is a VEGF receptor. There are three main subtypes of VEGFR, numbered 1, 2 and 3. All members of the VEGF family stimulate cellular responses by binding to
GTX00258-pro Functional Assay Image
SDS-PAGE analysis of GTX00258-pro Human VEGF Receptor 2 protein (active).
The inhibition effect of GTX00258-pro Human VEGF Receptor 2 protein (active) on VEGF-dependent proliferation. Cell viability was measured by Cell Counting Kit-8 (CCK-8). (A) Unstimulated ECV-304 cells cultured in DMEM for 96hrs. (B) ECV-304 cells cultured in DMEM, stimulated with 10 ng/ml VEGFR2 for 96hrs.
WB analysis of GTX00258-pro Human VEGF Receptor 2 protein (active).
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